Colonoscopy prep may be getting less horrible

The worst thing about having a colonoscopy isn’t when you’re sedated and your doc scopes you where the sun don’t shine. It’s the prep, when you have to drink a gross laxative — and lots of it — to evacuate your plumbing for a clear reading. So gross. I’ve been there, so I appreciate efforts to build a better bowel cleaner. ...

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RIP for the dreaded colonoscopy drink?

To clear the colon and rectum for doctors to examine them for early signs of cancer, patients must guzzle a gargantuan amount of a salty, repulsive-tasting drink and laxative. While there are many different brands of this drink available, most of them have the same “ick” factor. ...

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ColonaryConcepts Successfully Completes Phase 2 Study for a New Approach to Colonoscopy Prep for Colorectal Cancer Screening

ColonaryConcepts, LLC (CC) today announced positive topline results from a randomized, colonoscopist-blinded Phase 2 clinical study of the company’s novel investigational colonoscopy prep kit. The kit, to be available by prescription, is comprised of nutritionally balanced bars and beverages incorporating the standard purgative active ingredient, PEG 3350, which a patient consumes during the 24 hours prior to colonoscopy. Results of the study, ended after 65 patients completed a colonoscopy, showed successful colon cleansing (i.e., endoscopic visibility) in that over 90% of patients using the lead formulation had ‘excellent’ or ‘good’ rated colonoscopies. At the same time, participants reported high satisfaction with the CC kit and experienced no serious adverse events ...

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Newton startup seeks to purge the unpleasantness from colonoscopy prep

When Dr. Corey Siegel was doing his gastroenterology fellowship at Massachusetts General Hospital, he spotted a troubling trend: Patients were avoiding colonoscopies because the preparation ahead of the procedure was so grueling. Siegel, who now works at Dartmouth-Hitchcock Medical Center, and his MGH mentor, Dr. Joshua Korzenik, who is now director of Brigham and Women’s Hospital Crohn’s and Colitis Center, have since embarked on developing a new bar and beverage line to help people prep for colonoscopies. The goal, he says, is to provide a more palatable alternative to the salty, sludgy liquid patients must imbibe ahead of the procedure ...

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ColonaryConcepts Article

DDW: Scheduled for a colonoscopy? Pass the pretzels!

A novel, edible colon preparation could make obsolete the fasting and large volume of salty liquid cleansing that keep many a patient from completing their colonoscopies. A pilot study showed that all 10 patients who ate a series of nutritionally balanced meals, drinks, and snacks such as pretzels and pudding had a successful colon cleansing according to the endoscopist at the time of the procedure, Dr. L. Campbell Levy of Dartmouth-Hitchcock Medical Center in Lebanon, N.H., reported at the annual Digestive Disease Week...

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ColonaryConcepts Article

You may not have to drink that nasty liquid before your colonoscopy

There is general agreement that colonoscopies save lives. About 140,000 people will come down with colon or rectal cancers this year, according to the American Cancer Society, and about 50,000 people will die from those diseases. Yet an estimated 25 million people who should be screened don't have the procedure done. That's about 40 percent of the people who should...

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Bowel screening to become less of a pain in the backside

Preparing for a colonoscopy isn't fun. Patients must fast and drink litres of fluid laced with foul-tasting chemicals to clean out their bowels. The good news is that a more friendly alternative is in the pipeline. Researchers developing the approach believe a single day of specially prepared foods, with the necessary laxatives and electrolytes incorporated into the preparation, can do the cleansing job just as well as the traditional, gruelling approach...

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Colonoscopy Prep Made Palatable

Patients recommended for screening colonoscopy often resist because the bowel cleansing regimen is unpleasant. In an abstract presented May 17 at the 2015 Digestive Disease Week conference in Washington, DC, Campbell Levy, MD, of Dartmouth-Hitchcock Medical Center in Lebanon, NH, and colleagues at other institutions report on a novel edible product that achieves the desired results…

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Purgative Meals Touted as New Approach to Colonoscopy Prep

Arguably the worst part of colonoscopies for patients was made a bit easier with a new approach to bowel cleansing, a researcher reported here. In a small pilot study, meals infused with the conventional laxative agent PEG-3350 along with sorbitol and ascorbic acid, which patients consumed the day before screening or surveillance colonoscopies, provided good-to-excellent bowel cleansing according to the endoscopists' standard grading, with good-to-excellent tolerability ratings from the patients as well, according to L. Campbell Levy, MD, of Dartmouth-Hitchcock Medical Center in Lebanon, N.H...

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